1 - Milia-like cysts
2 - Comedo-like openings
3 - Exophytic papillary structures
4 - Red Lacunas
5 - Leaf-like areas
6 - Central White patch
Milia-like cysts
This typical example of seborrheic keratosis is characterized by numerous milia-like cysts (arrows) and few comedo-like openings
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Acanthotic seborrheic keratosis with several milia-like cysts (arrows) and few, variously shaped comedo-like openings
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This acanthotic type of seborrheic keratosis reveals rare, variously sized horn pseudocysts corresponding to milia-like cysts
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Comedo-like openings
This heavily pigmented seborrheic keratosis is characterized by numerous comedo-like openings (arrows). Only few milia-like cysts can be recognized.
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The comedo-like openings (arrows) of this seborrheic keratosis are only faintly colored, in contrast to the dark-stained comedo-like openings of the previous example. In addition, note few, large milia-like cysts in the lower left part of this lesion.
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Note few comedo-like openings and also some horn pseudocysts in this seborrheic keratosis
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Exophytic papillary structures
This papillomatous dermal nevus (Unna nevus) is characterized by several, closely aggregated exophytic papillary structures. Nearly identical papillations are commonly found also in seborrheic keratoses.
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Within the center of this Clark nevus several exophytic papillary structures are recognized
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This is a typical example of a papillomatous dermal nevus (Unna nevus) exhibiting a pronounced papillomatous appearance that corresponds to exophytic papillary structures
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Red Lacunas
Stereotypical example of hemangioma with numerous red-bluish lacunas
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Angiokeratoma with several red-violaceous to blue-black lacunas due to thrombosed vascular structures. Note that the blue-whitish veil in this angiokeratoma has no diagnostic significance.
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This high magnification of a typical hemangioma depicts the corresponding histopathologic finding of a given red lacuna
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Leaf-like areas
The clue for the diagnosis of this basal cell carcinoma is the presence of leaf-like areas (arrows) at the periphery of this lesion. Obviously one needs to have some visual imagination to recognize leaf-like structures!!
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Another example of basal cell carcinoma with numerous leaf-like areas (arrows) along the circumference of this lesion. Since no clear-cut pigment network is present, the blue whitish veil has no diagnostic significance.
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This superficial type of basal cell carcinoma is composed of large aggregations of basaloid cells some of which contain clusters of melanophages thus forming the so called leaf-like areas
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Central White patch
The central white patch represents the dermoscopic hallmark of dermatofibroma, as illustrated in this example
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Another example of typical dermatofibroma with a central white patch
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